When it comes to vaccination, people often wonder what time is the best to get it? Is it the Morning time or the afternoon? As per a recent study, time of the day also affects your immune response to Covid vaccination.
It further suggests that antibody levels are higher in people who take their shots later in the day. The research was published in the Journal of Biological Rhythms. It demonstrates that our internal 24-hour circadian clock regulates many aspects of physiology; this includes the response to infectious disease and vaccination.
“Our observational study also provides proof of concept that time of day affects the immune response to SARS-CoV-2 vaccination, findings that may be relevant for optimising the vaccine’s efficacy,” said study co-senior author Elizabeth Klerman from Massachusetts General Hospital (MGH), US.
Did you know that symptoms of some diseases and the action of numerous medications depend on the time of the day?
What’s The Best Time to get vaccinated?
For example, people with lung diseases frequently have greater symptom severity and altered respiratory function at certain times of the day.
Besides, the elderly men who received influenza vaccination had higher antibody titers when they received the jab in the morning as compared to the ones who got it in the afternoon.
This is the reason why researchers, including study authors, emphasise the role of circadian signalling in regulating SARS-CoV-2 immune responses and COVID-19 severity.
In order to reach a lasting consensus, more research is needed to replicate the findings of researchers.
Basically, there is a need to develop a better understanding of the underlying physiology of SARS-CoV-2 and the body’s response to vaccination.
But indeed this research is the first step in demonstrating the importance of time of the day response to SARS-CoV-2 vaccine jabs.
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