Sputnik V two doses give more than twice higher protection against Omicron

Sputnik V two doses give more than twice higher protection against Omicron
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A new study proves two doses of the Sputnik V vaccine provide more than twice higher protection against the Omicron variant.

The geometric mean titers (GMT) of virus-neutralising antibodies is strongly triggered by Sputnik V than two doses of Pfizer vaccine.

The study was published as a pre-print in medRxiv on January 19. The Gamaleya National Research Center of Epidemiology and Microbiology (Gamaleya Center) and the Russian Direct Investment Fund (RDIF, Russia’s sovereign wealth fund, investor in Sputnik V and Sputnik Light vaccines), also announced the study at a virtual media conference.

The study was conducted at the National Institute for Infectious Diseases Lazzaro Spallanzani (Italy) by a team of researchers of the Institute and the Gamaleya Center.

It shows that two doses of Sputnik V give more than two times higher geometric mean titers (GMT) of virus neutralising antibodies to the Omicron variant than two doses of Pfizer vaccine.

Sputnik V has been authorised in 71 countries with a total population of over 4 billion people.

Besides, Sputnik Light has been authorised in more than 30 countries.

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Although, this remains a preliminary laboratory study that was conducted in the Spallanzani Institute in Italy.

Comparable sera samples were used for the same from individuals who got vaccinated with Sputnik V and Pfizer with a similar level of IgG antibodies and virus-neutralizing activity (VNA) against the Wuhan variant.

As per the researchers, samples were taken three to six months after the second dose.

Another preliminary study conducted earlier by the Gamaleya Institute shows that a booster shot of the Sputnik Light vaccine provides a stronger antibody response against Omicron than the two-dose Sputnik V vaccine alone.

The Omicron variant of COVID-19 has surged the caseload to record highs. Parts of western Europe and the United States are struggling to bring the infection rates down.


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